One person was killed and two others suffered major injuries in a head-on crash on state Highway 29 southeast of Calistoga in Napa County, a California Highway Patrol spokesman said.
The two-vehicle crash was reported around 10:10 a.m. on Highway 29 in the area of Larkmead Lane.
The Napa County CHP Twitter account posted about the crash shortly after 11 a.m. and recommended using the Silverado Trail as an alternate route.
The driver of one car died in the crash and a passenger in that car suffered major injuries, while the driver and lone occupant of the other car also suffered major injuries, CHP Officer Marc Renspurger said.
The cause of the crash is under investigation and Highway 29 remained shut down in both directions in the area as of late morning. There is no estimated time to reopen the roadway.