Authorities said two people on a motorbike were killed in a traffic collision on Little Big Lane, east of Ramona.
The motorcycle collided with a significant off-road vehicle side-by-side at around 2:09 PM, according to Thomas Shots of Cal Fire San Diego.
Shoots said two people on the motorcycle were announced dead at the scene, and four people on the motorcycle were not injured.
Shots said four fire trucks from Cal and two ambulances responded to the site, along with California Highway Patrol units.
No further information was available about the accident.